ENDOCRINE DISEASES

So, now i am studying for tomorrow exam.

Finally, tomorrow will be the last day for mid term. But wait! Aha, final exam is coming in 4 weeks!! Basically, winter semester will be the hectic sem ever, but its okay. I am still enjoying my crazy weird life though.

Okay, just now, i  revised about estrogens and their agonists hormones, their clinical uses etc.

First of all, based on previous knowledge, hormones will bind to hormone receptors and they are the member of Nuclear Receptor Superfamily which are subdivided into 3 more categories:-

i) Class I Nuclear receptor (NR)
ii) Class II NR
iii) Orphan

Estrogens can give their effect on endometrium,breast, bone, skeletal muscle, cardiovascular system, and central nervous system.

There are few types of  estrogens agonist. And again, agonists can be subdivided into full/ strong agonist, partial agonist or weak agonist.

Okay, so back to the concept, WHAT ARE ESTROGEN AGONISTS? (i.e substances that can mimic the action of estrogens?

Again, haha, ot can be subdivided into 3 classes.

i) natural agonist (estradiol estriol, estrone)
ii) synthetic estrogens (ethinyl estradiol, mestranol)
iii) non streoidal estrogens (diethylsyillbesterol)


Huh, crazy enough ha? relax, this is just 0.00000000000001 % of what we have to know in total =.=

I just wanna be cool. Like this. haha